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pentobarbital will decrease the extent or result of etravirine by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Observe.Contraindicated (1)pentobarbital decreases levels of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can lower panobinostat amounts by ~70% and cause the